Cinnamic acids and derivatives
Medchemexpress LLC (4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one | 100667-52-5 | 97.0% | 280.36 g/mol | C19H20O2 | 5 MG
(4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one is a diarylheptanoid small-molecule for laboratory research and analytical applications. The compound is supplied as a solid with molecular formula C19H20O2, molecular weight 280.36 g/mol, and an analytical purity of 97.0% (NMR). Store protected from light at low temperatures; consult the certificate of analysis for batch-specific handling and stability information.
- Solid, white to off-white appearance.
- Molecular formula C19H20O2.
- Molecular weight 280.36 g/mol.
- Analytical purity 97.0% (NMR).
- Storage: keep container tightly sealed, protect from light; recommended -20°C for solid, in solvent -80°C for 6 months or -20°C for 1 month.
- Intended for research and analytical use only; not for human therapeutic use.
Medchemexpress LLC (E)-Ferulic acid | 537-98-4 | 99.9% | 194.19 | 1 ML
(E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound found in plant cell walls. It causes phosphorylation of β-catenin, leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax, and reducing the expression of the survival factor survivin. It can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation, and exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.
- Removes reactive oxygen species (ROS)
- Inhibits lipid peroxidation
- Exerts antiproliferative effects in human lung cancer cells
- Exerts antimigratory effects in human lung cancer cells
- Induces phosphorylation and proteasome degradation of β-catenin
- Increases expression of pro-apoptotic factor Bax
- Reduces expression of the survival factor survivin
- Reduces liver and kidney toxicity and oxidative stress
Selleck Chemical LLC Curcumin analog C1
Curcumin analog C1 (Curcumin analog Compound C1) is a potent transcription factor EB (TFEB) activator with promise for the prevention or treatment of Alzheimer s disease
Medchemexpress LLC Entacapone | 130929-57-6 | MFCD00866580 | >98.0% | 305.29 g/mol | C14H15N3O5 | 5 MG
Entacapone is a research-grade catechol-O-methyltransferase (COMT) inhibitor supplied as a small-scale reagent. It is potent, reversible, peripherally acting, and orally active, and is used in Parkinson's disease research and studies of FTO demethylation.
- Potent, reversible COMT inhibitor.
- Peripherally acting and orally active.
- Suitable for Parkinson's disease research.
- Inhibits FTO demethylation for metabolic research.
- Purity >98.0% (HPLC) reported by suppliers.
- Molecular formula C14H15N3O5; molecular weight 305.29 g/mol.
- Supplied as a small-scale research pack (5 mg).
eMolecules Pharmablock / methyl (1S3R)-3-hydroxycyclopentanecarboxylate / 25mg / 586161437 / PBSQ500088 / 0.000 / 1292307-06-2 / MFCD29925513 / 144.170 / C7H12O3
Pharmablock / methyl (1S3R)-3-hydroxycyclopentanecarboxylate / 25mg / 586161437 / PBSQ500088 / 0.000 / 1292307-06-2 / MFCD29925513 / 144.170 / C7H12O3
Apexbio Technology LLC (E,E)-Bisdemethoxycurcumin 33171-05-0 5mg
(E E)-Bisdemethoxycurcumin (CAS 33171-05-0) is a naturally derived curcuminoid and a structural analog within the demethoxycurcumin class Research demonstrates that this compound modulates multiple inflammatory signaling pathways and alters the expression of various inflammatory mediators It has been shown to induce cell cycle arrest promote apoptosis in cancer cells and inhibit proliferation-related pathways (E E)-Bisdemethoxycurcumin is widely utilized in studies investigating the molecular mechanisms of inflammation tumor cell biology and the pharmacological properties of curcuminoid derivatives
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.07% | 274.25 | 50 MG
Ferulic acid 4-O-sulfate is a metabolite of Ferulic acid that relaxes arteries and lowers blood pressure in mice. This compound causes significant concentration-dependent relaxations in mouse aorta, femoral and saphenous arteries.
- Relaxes arteries and lowers blood pressure
- Suitable for in vitro and in vivo studies
- Significant concentration-dependent relaxations in mouse arteries
Medchemexpress LLC Curcumin 5-8 | 890984-26-6 | 98.58% | 339.39 | 100 MG
Curcumin 5-8 is a potent, orally active curcumin analog. It inhibits lipid droplet formation, increases autophagy, and inhibits apoptosis. It also improves insulin resistance and insulin sensitivity, and has been shown to ameliorate nonalcoholic fatty liver disease in mice.
- Decreases PA-induced SREBP1 expression and increases Bcl2/BAX expression in AML12 cells.
- Exhibits cytotoxic activity against B16, HUVEC, SiHa, U-87MG ATCC, and Vero cell lines.
- Ameliorates insulin resistance and hepatic steatosis in HFD-induced obese mice.